Table 3.
Clinical neurological outcome for children with congenital hyperinsulinism.
| Total | Scandinaviana | Referred non-Scandinavianb | Russianc | |
|---|---|---|---|---|
| Cerebral palsy, n = 75 | 10 (13%) | 1 (7%) | 6 (18%) | 3 (11%) |
| Visual impairment, n = 75 | 4 (5%) | 0 (0%) | 1 (4%) | 3 (11%) |
| Epilepsy, n = 75 | 17 (23%) | 2 (13%) | 6 (18%) | 9 (33%) |
| Microcephaly, n = 39 | 6 (15%) | 1 (7%) | 5 (15%) | N/A |
| Electroencephalography, n = 55 | ||||
| Normal | 42 (76%) | 3 (75%) | 16 (48%) | 23 (85%) |
| Abnormal | 13 (24%) | 1 (25%) | 6 (18%) | 6 (22%) |
| MRI of the brain, n = 40 | ||||
| Normal | 21 (53%) | 5 (33%) | 11 (33%) | 5 (19%) |
| General atrophy | 9 (23%) | 1 (7%) | 7 (21%) | 1 (4%) |
| White matter changesd | 11 (28%) | 1 (7%) | 8 (24%) | 2 (7%) |
aChildren born, treated and tested in Scandinavia.
bChildren from Eastern Europe/Russia, tested and further treated in Denmark.
cChildren from Russia, tested and treated in Russia.
dReduced myelinization or hypoglycemic encephalopathy.