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. Author manuscript; available in PMC: 2017 Jul 10.
Published in final edited form as: ACS Chem Biol. 2016 Mar 8;11(5):1383–1390. doi: 10.1021/acschembio.5b01069

Table 2.

Intrinsic KIEs for Saporin and Ricin

10-mer saporin with RNA ricin with RNAa ricin with DNAb
[1′-14C], [5′-3H] 1.052 ± 0.008 0.993 ± 0.004 1.015 ± 0.001
[9-15N, 1′-14C], [5′-3H] 1.064 ± 0.009 1.012 ± 0.004
[1′-3H], [5′-14C] 1.045 ± 0.004 1.163 ± 0.009 1.187 ± 0.008
[4′-3H], [5′-14C] 0.960 ± 0.004 0.992 ± 0.004
[5′-3H], [5′-14C] 1.041 ± 0.006 0.996 ± 0.003 1.014 ± 0.004
[7-15N, 5′-14C], [5′-3H] 0.973 ± 0.007 0.981 ± 0.008
[9-15N, 5′-14C], [5′-3H] 1.023 ± 0.009 1.016 ± 0.005 1.023 ± 0.004
a

Values taken from Chen et al.48

b

Values taken from Chen et al.49