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Effects of CNIs in IL-2 and IL-7 signaling. (A) STAT5 phosphorylation analysis of CD4+ T-cell subsets of liver transplant patients (n = 18) after culture of PBMCs for 30 min in various concentrations of IL-2. (B) Correlation between CD127 and CD25 expression in healthy controls (HC, n = 25). (C) STAT5 phosphorylation analysis of Treg subsets in liver transplant patients (n = 18) after culture of PBMCs for 30 min in increasing concentrations of IL-7.
