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. 2017 Jun 19;114(27):6942–6947. doi: 10.1073/pnas.1702650114

Fig. 3.

Fig. 3.

Crossing-only severing is essential for alignment if induced catastrophes are rare, but is insufficient if they are absent. Bundling occurs for θ<40°. (A) Without severing, the reduced induced catastrophe probability Pcat=0.09 is insufficient to find an aligned regime. (B) With high severing (rx=0.1s1), some degree of alignment occurs over the same range of parameters for all three values of Pcat. (C) Using optical instead of normal S2 to measure alignment, i.e., counting every stretch of MT bundle as a single MT, regardless of the actual number in the bundle, alignment disappears toward Gc=0 in the absence of induced catastrophes. Also, for intermediate values of Gc, the arrays would appear poorly aligned. Error bars represent SEM, with n = 100 independent simulations per data point. For other values of rx and buildup of alignment over time, see SI Appendix, Figs. S6–S8.