Fig. 5.
LYR–ACP interactions identified in the SDAec complex appear conserved for the LYR superfamily of proteins. (A) Structural overlay of ISD11–ACP (wheat and salmon) with LYRM3–ACP (limon and deep salmon) and LYRM6–ACP (sand and warm pink) from bovine complex I (PDB ID code 4UQ8). (B) Sequence conservation of the 11 human LYR proteins mapped onto ISD11–ACP of the SDAec structure. Similar sequence conservation of ACPec and human mitochondrial ACP is also mapped to ISD11–ACP. Consurf scores, indicating relative conservation, are displayed in the scale bar.