Table 1.

Elastic constants determined from microsecond-long MD simulations of dsDNA and dsRNA and the constitutive equations of the elastic rod model

Elastic parameter	dsDNA (this work)	dsDNA (exp. work)	dsDNA refs.	dsRNA (this work)	dsRNA (exp. work)	dsRNA refs.
$S$, pN	1,280 ± 70	1,450 to 1,750	(32, 33)	480 ± 11
$\stackrel{\sim }{S}$, pN	1,120 ± 50	649 to 1,401	(5, 6, 42–44)	416 ± 7	350,500	(5, 6)
$C$, pN⋅nm2	303 ± 23	386 to 448	(5, 45–47)	310 ± 24	409	(5)
$g/k_{B}T$, no units	−54 ± 3	–17 to –39	(2, 5, 32, 33, 41, 46)	34 ± 1	11.5	(5)

The constitutive equations of the elastic rod model are shown in Eqs. 2–4. These equations allow us to compute all elastic parameters from the slopes of Fig. 2 A and B and from the helical rise-helical twist slopes computed for each force (SI Appendix, Fig. S3). Quoted errors represent deviations from the linear fits. Constants obtained in this work are compared with other experimental (exp.) work.