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. Author manuscript; available in PMC: 2018 Feb 28.
Published in final edited form as: Biochemistry. 2017 Feb 16;56(8):1140–1150. doi: 10.1021/acs.biochem.6b01030

Figure 6. Close-up view of the PBP2 region near the A501T mutation.

Figure 6

Superimposition of molecule B of wild-type PBP2 (3EQU; blue) and molecule B of PBP2-6140CT-A501T (orange). Cefuroxime has been docked into the wild-type structure based on the structure of the acylated PBP2x from S. pneumoniae (1QMF).