Table 1.
Clinicopathologic characteristics of SPCRP analyzed in this study.
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clinical findings | |||||||||||||
| Age, y | 68 | 62 | 63 | 79 | 64 | 51 | 64 | 58 | 66 | 65 | 70 | 65 | 65 |
| Laterality | L | L | L | R | R | R | L | R | R | L | L | L | L |
| Size, cm | 0.9 | 0.8 | 1.2 | U | 1.8 | 0.8 | 1.4 | 0.6 | 0.9 | 1.5 | 1.3 | 1.2 | 0.9 |
| LN metastasis/ sampled | U | 0/2 | NP | U | 0/2 | 0/3 | 0/1 | U | 0/3 | 0/2 | 0/2 | 0/4 | U |
| Outcome/mo | U | NED/77 | U | U | NED/31 | NED/30 | NED/29 | U | NED/20 | NED/37 | NED/12 | U | U |
| Treatment | U | S/XRT | U | U | U | S | S/XRT | U | S/C | S/XRT/C | U | U | U |
| Cancer history | U | + | U | U | - | + | - | U | - | - | - | U | U |
| Immunohistochemical features | |||||||||||||
| CK5/6 | + | + | + | + | + | + | Rare + | - | + | + | Focal + | Focal + | + |
| CK7 | + | + | + | + | + | + | + | + | + | - | + | + | NP |
| CK 34βE12 | NP | + | + | + | + | + | - | + | + | + | + | + | NP |
| CK AE1/AE3 | NP | + | NP | + | + | NP | + | + | + | + | + | + | NP |
| p63 | - | - | - | - | - | - | - | - | - | - | - | - | - |
| SMMHC | - | - | - | - | - | - | - | - | - | - | - | NP | - |
| Calponin | - | - | - | - | - | - | - | - | - | NP | - | - | NP |
| ER | - | - | <10% + | - | - | <10% + | <10% + | - | - | <10% + | <10% + | - | - |
| PR | - | - | <10% + | - | - | <10% + | - | - | - | - | - | - | - |
| HER2 | NP | - | NP | NP | - | - | - | - | - | - | - | - | - |
| AR | NP | - | - | - | - | - | - | - | - | NP | - | - | Focal + |
| GCDFP-15 | Focal + | - | Focal + | Focal + | Focal + | Focal + | - | - | Focal + | - | Focal + | - | Focal + |
| Mammaglobin | Focal + | + | Focal + | Focal + | Focal + | - | - | - | - | - | Focal + | + | NP |
| TTF-1 | - | - | NP | - | - | - | - | - | - | - | - | - | - |
| Thyroglobulin | NP | - | NP | - | - | NP | - | - | - | - | - | - | - |
Abbreviations: AR, androgen receptor; C, chemotherapy (carboplatin and taxol); CK, cytokeratin; ER, estrogen receptor; GCDFP-15; gross cystic disease fluid protein-15; L, left; LN, lymph node; mo, months; NED, no evidence of disease; NP, not performed; R, right; SMMHC, smooth muscle myosin heavy chain; TTF-1, thyroid transcription factor-1; U, unknown; XRT, radiation; y, years