Functional brain connectivity. Group mean data are normalized r values computed from the correlation between mean BOLD signal in the seeded region (green) and all other brain regions and averaged within each group (top panel) (A) Hippocampus seed; (B) Sham/VEH; (C) FPI/VEH; (D) FPI/Exc; (E) FPI/7,8-DHF and (F) FPI/Exc/7,8-DHF. Voxel-based, statistical contrast (bottom panel) between (G) FPI/VEH vs Sham/VEH; (H) FPI/7,8-DHF vs FPI/VEH; (I) FPI/Exc vs FPI/VEH; (J) FPI/7,8-DHF/Exc vs FPI/VEH (z = 1.7, P < 0.05, unpaired t-test). Scalebar = Z threshold.