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. 2017 Jun 19;9(7):465–479. doi: 10.1177/1758834017711097

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© The Author(s), 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).

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Figure 1. — A schematic representation comparing the action of oestradiol (E) with that of tamoxifen (T) and fulvestrant (F).

AF1, activation function 1; AF2, activation function 2; E, oestradiol; ER, oestrogen receptor; ERE, oestrogen receptor response element; F, fulvestrant; RNA POL II, ribonucleic acid polymerase II; T, tamoxifen.