Table 1.

List of Capsid Amino Acid Substitutions Utilized in This Study

Mutant Name	Amino Acid Mutations
AAV2
T2 WT	N/A
T2 1Y	Y444F
T2 3Y	Y444F, Y500F, Y730F
T2 2Y #1	Y500F, Y730F
T2 2Y #2	Y444F, Y730F
T2 6Y	Y252F, Y272F, Y444F, Y500F, Y704F, Y730F
T2 3Y +T	Y444F, Y500F, Y730F, T491V
T2 4Y + T	Y272F, Y444F, Y500F, Y730F, T491V
T2 3Y +T +dH	Y444F, Y500F, Y730F, T491V, R585S, R588T, R487G
T2 3Y +dH	Y444F, Y500F, Y730F, R585S, R588T, R487G
AAV5
T5 WT	N/A
T5 1Y	Y719F
T5 2Y	Y263F, Y719F
T5 5Y	Y242F, Y263, Y689F, Y693F, Y719F
AAV8
T8 WT	N/A
T8 1Y	Y733F
T8 2Y	Y447F, Y733F
T8 2Y +T	Y447F, Y733F, T494V

dH, abolished heparin sulfate binding domain; F, phenylalanine; G, glycine; S, serine; T, threonine; V, valine; WT, wild-type; Y, tyrosine.