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Simplified schematic diagram of the three cortico-basal-ganglia loops, including indications of glutamate, GABA, and dopamine neuron projections; A) limbic loop, B) associative loop, C) sensorimotor loop. Dorsal Medial Striatum (DMS), Dorsal Lateral Striatum (DLS), Globus Pallidus external segment (GPe), Nucleus Accumbens (NAc) Substantia Nigra pars reticulata (SNr), Substantia Nigra pars compacta (SNpc), Ventral Pallidum (VP), and Ventral Tegmental Area (VTA).
