Table 2. Stage specific multivariate analysis.
OS and DFS with the corresponding HR for every 2-unit increase in the NLR value among patients with colon cancer. The adjusted HR for every 2 unit increase in NLR value is significant for resectable colon cancer within the first 2 and 5 years of diagnosis.
Increments by 2 Units | ||||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
Stage | Number of Patients | Events | 5-yr OS% | HR | Lower | Upper | P-value | |
|
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5 year | I | 454 | 80 | 82.4 | 1.27 | 1.10 | 1.47 | 0.001573 |
II | 555 | 101 | 81.8 | 1.17 | 1.07 | 1.28 | 0.000653 | |
III | 603 | 141 | 76.6 | 1.21 | 1.08 | 1.36 | 0.001138 | |
I,II, and III | 1612 | 322 | 80.0 | 1.19 | 1.12 | 1.27 | < 0.0001 | |
Stage | Number of Patients | Events | 5-yr DFS% | HR | Lower | Upper | P-value | |
|
||||||||
5 year | I | 454 | 72 | 84.1 | 1.25 | 1.08 | 1.45 | 0.003411 |
II | 555 | 104 | 81.3 | 1.15 | 1.05 | 1.27 | 0.003205 | |
III | 604 | 157 | 74.0 | 1.19 | 1.05 | 1.35 | 0.006338 | |
I,II, and III | 1613 | 333 | 79.4 | 1.16 | 1.09 | 1.24 | < 0.0001 | |
|
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Stage | Number of Patients | Events | 2-yr OS% | HR | Lower | Upper | P-value | |
|
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2 year | I | 454 | 49 | 89.2 | 1.22 | 0.99 | 1.51 | 0.060675 |
II | 555 | 50 | 91.0 | 1.22 | 1.08 | 1.37 | 0.000886 | |
III | 603 | 83 | 86.2 | 1.29 | 1.13 | 1.46 | 0.000111 | |
I,II, and III | 1612 | 182 | 88.7 | 1.26 | 1.16 | 1.36 | < 0.0001 | |
Stage | Number of Patients | Events | 2-yr DFS% | HR | Lower | Upper | P-value | |
| ||||||||
2 year | I | 454 | 40 | 91.2 | 1.21 | 0.99 | 1.49 | 0.065303 |
II | 555 | 53 | 90.5 | 1.17 | 1.03 | 1.32 | 0.013472 | |
III | 604 | 102 | 83.1 | 1.25 | 1.09 | 1.43 | 0.001395 | |
I,II, and III | 1613 | 195 | 87.9 | 1.20 | 1.10 | 1.30 | < 0.0001 |