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. 2017 Jun 30;22(2):74–81. doi: 10.15430/JCP.2017.22.2.74

Figure 4.

Figure 4

The potential BCR-ABL1–dependent molecular mechanisms leading to chronic myeloid leukemia disease progression (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898591/). BAD, BCL2 antagonist of cell death; DNA-PKcs, DNA-dependent protein kinase, catalytic subunit; FOXO, fork head box O; IK6, Ikaros 6; miR-328, microRNA-328; MLH1, mutL homolog 1; PMS2, post meiotic segregation increased 2; RAD51, RecA homolog in Escherichia coli; RAD52, RAD52 homolog (Saccharomyces cerevisiae); Shh, Sonic Hh; wnt/β-catenin, wingless-int1/beta-catenin.