Table 2.
Comparison of species frequency of gastric antrum and body mucosal samples
| Phylum | Species | Antrum (%) | Body (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| HP(−) control (n = 2) | HP(−) cancer (n = 2) | HP(+)control (n = 3) | HP(+)cancer (n = 5) | HP(−) control (n = 2) | HP(−) cancer (n = 2) | HP(+)control (n = 3) | HP(+)cancer (n = 5) | ||
| Firmicutes | Streptococcus pseudopneumoniae | 0.14 | 18.68a | 3.37a | 6.04a | 3.80a | 23.11a | 0.98 | 0.20 |
| S. mitis | 0.02 | 9.01a | 0.51 | 0.82 | 0.45 | 3.09a | 0.23 | 0.00 | |
| S. salivarius | 0.01 | 4.00a | 0.11 | 0.40 | 0.27 | 6.37a | 0.03 | 0.02 | |
| S. infantis | 0.32 | 3.39a | 0.24 | 1.10a | 3.07a | 5.38a | 0.08 | 0.12 | |
| Veillonella atypica | 0.03 | 2.97a | 0.23 | 0.64 | 0.32 | 1.22a | 0.03 | 0.01 | |
| V. dispar | 0.03 | 2.37a | 0.18 | 0.77 | 0.53 | 1.25a | 0.05 | 0.01 | |
| Granulicatella adiacens | 0.04 | 3.33a | 0.08 | 0.71 | 0.51 | 1.98a | 0.03 | 0.02 | |
| Gemella haemolysans | 0.00 | 2.09a | 0.19 | 0.20 | 0.03 | 1.16a | 0.05 | 0.01 | |
| S. australis | 0.05 | 2.19a | 0.14 | 0.68 | 0.59 | 2.01a | 0.10 | 0.01 | |
| S. parasanguinis | 0.14 | 1.51a | 0.27 | 0.60 | 0.86 | 3.36a | 0.14 | 0.04 | |
| S._uc | 0.10 | 1.14a | 0.20 | 0.65 | 0.76 | 2.96a | 0.06 | 0.06 | |
| GQ130066_s | 0.01 | 0.90 | 0.21 | 0.54 | 0.00 | 0.00 | 0.00 | 0.00 | |
| S. oralis | 0.02 | 1.72a | 0.14 | 0.30 | 0.50 | 2.07a | 0.08 | 0.01 | |
| Lactobacillus salivarius | 0.00 | 1.93a | 0.00 | 0.05 | 0.01 | 0.67 | 0.00 | 0.00 | |
| S. tigurinus | 0.01 | 1.06a | 0.03 | 0.17 | 0.25 | 0.43 | 0.00 | 0.00 | |
| Solobacterium moorei | 0.02 | 0.17 | 0.03 | 0.54 | 0.01 | 0.13 | 0.00 | 0.02 | |
| S. lactarius | 0.02 | 0.88 | 0.05 | 0.08 | 0.14 | 0.65 | 0.02 | 0.00 | |
| Megasphaera micronuciformis | 0.00 | 0.70 | 0.02 | 0.15 | 0.03 | 0.04 | 0.00 | 0.00 | |
| Streptococcaceae_uc_s | 0.02 | 0.41 | 0.10 | 0.11 | 0.57 | 1.90a | 0.12 | 0.05 | |
| Lactobacillales_uc_s | 0.01 | 0.19 | 0.02 | 0.08 | 0.82 | 2.09a | 0.07 | 0.05 | |
| Proteobacteria | HP | 0.11 | 0.11 | 86.47a | 60.30a | 0.42 | 0.10 | 89.78a | 75.93a |
| Haemophilus parainfluenzae | 0.15 | 3.84a | 0.46 | 0.96 | 2.15a | 2.41a | 0.13 | 0.02 | |
| Escherichia coli group | 0.03 | 0.00 | 0.00 | 1.46a | 0.00 | 0.01 | 0.00 | 0.05 | |
| H. paraphrohaemolyticus | 0.00 | 1.60a | 0.08 | 0.60 | 0.03 | 1.10a | 0.02 | 0.01 | |
| Methylobacterium adhaesivum | 0.06 | 2.22a | 0.12 | 0.56 | 0.06 | 0.00 | 0.00 | 0.05 | |
| Bradyrhizobium jicamae | 0.00 | 0.07 | 0.01 | 0.22 | 8.66a | 0.68 | 0.24 | 1.24a | |
| Neisseria perflava | 0.00 | 4.24a | 1.14a | 0.17 | 0.04 | 5.12a | 0.04 | 0.02 | |
| Pseudomonas beteli | 1.05a | 0.05 | 0.01 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | |
| P. hibiscicola | 44.87a | 0.06 | 0.24 | 0.17 | 0.00 | 0.02 | 0.00 | 0.01 | |
| Helicobacteraceae_uc_s | 0.01 | 0.00 | 0.08 | 0.07 | 0.06 | 0.03 | 1.28a | 0.49 | |
| H._uc | 0.00 | 1.00a | 0.07 | 0.11 | 0.09 | 0.86 | 0.04 | 0.00 | |
| Aggregatibacter segnis | 0.02 | 1.07a | 0.00 | 0.05 | 0.00 | 0.44 | 0.00 | 0.01 | |
| H. haemolyticus | 0.00 | 0.61 | 0.10 | 0.04 | 0.04 | 0.53 | 0.04 | 0.00 | |
| Ralstonia pickettii | 45.90a | 0.05 | 0.02 | 0.04 | 0.03 | 0.00 | 0.00 | 0.00 | |
| Pasteurellaceae_uc_s | 0.01 | 0.19 | 0.02 | 0.03 | 0.36 | 0.69 | 0.02 | 0.01 | |
| Pasteurellales_uc_s | 0.00 | 0.04 | 0.01 | 0.02 | 0.12 | 0.63 | 0.00 | 0.01 | |
| B. pachyrhizi | 0.00 | 0.01 | 0.00 | 0.03 | 5.33a | 0.49 | 0.11 | 0.70 | |
| Klebsiella pneumoniae | 0.00 | 0.07 | 0.00 | 1.05a | 0.00 | 0.02 | 0.00 | 0.03 | |
| Neisseriaceae_uc_s | 0.00 | 0.22 | 0.00 | 0.02 | 0.05 | 0.60 | 0.00 | 0.00 | |
| Neisseriales_uc_s | 0.01 | 0.05 | 0.01 | 0.01 | 0.08 | 0.80 | 0.00 | 0.00 | |
| FJ269053_s | 0.02 | 0.08 | 0.00 | 0.01 | 14.23a | 1.38a | 0.46 | 2.94a | |
| B. denitrificans | 0.00 | 0.07 | 0.00 | 0.00 | 1.14a | 0.09 | 0.03 | 0.10 | |
| U87765_s | 0.02 | 0.02 | 0.00 | 0.00 | 2.97a | 0.27 | 0.08 | 0.51 | |
| Bradyrhizobiaceae_uc_s | 0.00 | 0.00 | 0.00 | 0.01 | 0.98 | 0.20 | 0.04 | 0.13 | |
| DQ532251_g_uc | 0.00 | 0.00 | 0.00 | 0.00 | 0.79 | 0.09 | 0.03 | 0.18 | |
| Pelomonas saccharophila | 0.00 | 0.00 | 0.00 | 0.00 | 3.26a | 0.47 | 0.22 | 0.95 | |
| Rhizobium hainanense | 0.00 | 0.00 | 0.00 | 0.00 | 1.10a | 0.11 | 0.04 | 0.24 | |
| M. longum | 0.00 | 0.00 | 0.00 | 0.00 | 1.91a | 0.09 | 0.06 | 0.40 | |
| M. radiotolerans | 0.01 | 0.00 | 0.00 | 0.00 | 3.08a | 0.18 | 0.11 | 0.62 | |
| B._g1_uc | 0.00 | 0.00 | 0.00 | 0.00 | 0.72 | 0.09 | 0.02 | 0.09 | |
| Bacteroidetes | Prevotella histicola | 0.01 | 3.08a | 0.11 | 0.43 | 0.11 | 1.85a | 0.08 | 0.00 |
| P. melaninogenica | 0.01 | 1.56a | 0.06 | 0.84 | 0.14 | 0.92 | 0.04 | 0.02 | |
| P._uc | 0.01 | 1.07a | 0.23 | 0.31 | 0.21 | 0.98 | 0.06 | 0.01 | |
| P. pallens | 0.02 | 0.65 | 0.08 | 0.33 | 0.03 | 0.31 | 0.00 | 0.02 | |
| P. salivae | 0.00 | 0.78 | 0.06 | 0.14 | 0.05 | 0.46 | 0.02 | 0.01 | |
| EF123551_g_uc | 0.00 | 0.00 | 0.00 | 0.00 | 1.45a | 0.11 | 0.07 | 0.51 | |
| Actinobacteria | Propionibacterium acnes | 1.43a | 0.42 | 0.82 | 4.42a | 8.49a | 1.39a | 0.27 | 4.34a |
| Actinomyces odontolyticus | 0.05 | 1.31a | 0.17 | 0.89 | 0.44 | 0.95 | 0.12 | 0.03 | |
| Rothia mucilaginosa | 0.09 | 0.26 | 0.07 | 0.12 | 0.90 | 0.09 | 0.05 | 0.01 | |
| Propionibacterium_uc | 0.02 | 0.01 | 0.01 | 0.04 | 0.53 | 0.07 | 0.01 | 0.07 | |
| Propionibacteriaceae_uc_s | 0.04 | 0.00 | 0.00 | 0.02 | 0.79 | 0.18 | 0.04 | 0.16 | |
| Viridiplantae | Prunus persica | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.03 | 0.83 |
| Nicotiana tabacum | 0.00 | 0.00 | 0.00 | 0.00 | 1.09a | 0.00 | 0.00 | 0.05 | |
| Ipomoea purpurea | 0.00 | 0.00 | 0.00 | 0.00 | 1.59a | 0.00 | 0.00 | 0.00 | |
| Fusobacteria | Fusobacterium nucleatum | 0.09 | 0.92 | 0.26 | 0.11 | 0.33 | 0.16 | 0.08 | 0.03 |
Values are presented as mean percent. HP, Helicobacter pylori.
a
This means cut off > 1.0.