Table 2. Screened cardiomyopathy related pathways and genes according to the result of chip.
Cardiomyopathy related pathways | Changes in genes |
---|---|
Regulation of actin cytoskeleton | Itgb7, Itgam, Itga4, Itgal, Vav1, Itgb2, Pik3r3, Pak1, Cyfip2, Iqgap2, Was, Itgb8, Myl7 |
HIF-1 signaling pathway | Timp1, Hk3, Cybb, Pik3r3, Cdkn1a, Nox1, Nppa |
Focal adhesion | Itgb7, Itga4, Vav1, Spp1, Figf, Pik3r3, Pak1, Tnc, Itgb8, Myl7, |
Tight junction | Cldn2, Cldn4, Hcls1, Prkci, Magi2, Myl7, |
Hypertrophic cardiomyopathy (HCM) | Itgb7, Cacna1d, Itga4, Cacng2, Itgb8 |