Table 3.
Correlation between genotype frequencies of TCF21 rs12190287 C>G and clinical features in osteosarcoma individuals.
| Variables | n | CC n (%) | CG n (%) | GG n (%) | P |
|---|---|---|---|---|---|
| Location | |||||
| Trunk | 28 | 13 (46.43) | 13 (46.43) | 2 (7.14) | 0.385 |
| Limbs | 197 | 74 (37.56) | 98 (49.75) | 25 (12.69) | |
| Ennecking stages | |||||
| IA or IB | 32 | 18 (56.25) | 11 (34.38) | 3 (9.38) | 0.032* |
| IIA or IIB or III | 193 | 64 (33.16) | 96 (49.74) | 33 (17.10) | |
| Operation | |||||
| Amputation | 38 | 14 (36.84) | 19 (50.00) | 5 (13.16) | 0.328 |
| Limb salvage | 187 | 73 (39.03) | 86 (45.99) | 28 (14.97) | |
| Metastasis | |||||
| Yes | 40 | 11 (27.50) | 18 (45.00) | 11 (27.50) | 0.037* |
| No | 185 | 74 (40.00) | 90 (48.65) | 26 (11.35) | |
*
Statistically significant (P<0.05)