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. 2017 Jul 10;12(7):e0180372. doi: 10.1371/journal.pone.0180372

Fig 2. OdDHL has a cell-specific and differential impact on MCF-DCIS.com cells dependent on culture condition.

Fig 2

Significant differences in mean MCF-DCIS.com viability relative to the control at 100, 200 and 400 μM OdDHL concentrations in hypoxia and normoxia in 2D (A) and 3D and 2D in normoxia (B); *** = p-value < 0.0001, ** = p-value < 0.01, * = p-value < 0.05 based on Tukey post-hoc differences. Significant differences in MCF-DCIS.com viability relative to the control between culture conditions with 400 μM OdDHL treatment in hypoxia and normoxia in 2D (C) and 3D and 2D in normoxia (D); *** = p-value < 0.0001 based on least mean contrasts. Significant differences in mean MCF-10A, MCF-DCIS.com, MDA-MB-231 viabilities relative to the control at 400 μM OdDHL concentrations in hypoxia and normoxia in 2D (E) and 3D and 2D in normoxia (F); *** = p-value < 0.0001 based on Tukey post-hoc differences. Error bars represent standard error of the mean.