Figure 2.

Brain activation maps during the balloon distension vs rest condition for (A) constipation-predominant irritable bowel syndrome (IBS-C) patients, (B) diarrhea-predominant irritable bowel syndrome (IBS-D) patients, (C) IBS-C and IBS-D patients, and (D) healthy controls at a threshold of P < 0.05, corrected for multiple comparisons (family wise error rate), spatial extent k = 10 voxels. SMA, supplementary motor area; MTG, middle temporal gyrus; FG, fusiform gyri; SMG, supra-marginal gyrus; Inf. OFC, inferior orbito-frontal cortex; SPL, superior parietal lobule.