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. 2017 Jul 1;23(3):415–427. doi: 10.5056/jnm16148

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© 2017 The Korean Society of Neurogastroenterology and Motility

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Regions which showed relatively more cerebral activation for the balloon distension vs rest condition in (A) irritable bowel syndrome (IBS) patients compared with healthy controls, (second level ANOVA, P < 0.001 uncorrected, spatial extent k = 10 voxels), (B) healthy controls compared with IBS patients, (C) constipation-predominant IBS (IBS-C) compared with diarrhea-predominant IBS (IBS-D) patients, and (D) IBS-D compared with IBS-C patients. Second level ANOVA, P < 0.01 uncorrected, spatial extent k = 10 voxels. MTG, middle temporal gyrus; Inf. OFC, inferior orbito-frontal cortex; SPL, superior parietal lobule; FG, fusiform gyri; SMA, supplementary motor area.