Ampullary carcinomas are immunohistchemically classified into intestinal-type or pancreatobiliary-type (or ambiguous-type). The top bar plot shows the number of somatic mutations among 92 genes for tumors from each case. The bottom left plot shows the mutation count for each individual gene. The bottom right bar plot shows the significance of each gene on –log10 (q) values. MS, missense mutation; NS, nonsense mutation; ESS, essential splice-site mutation (the first or last 2 bp of an intron); FS indel, frameshift insertion or deletion; IF indel, in-frame insertion or deletion.
See also Figure S2 and Tables S2, S5, and S10.