Table 1.

Study Demographics and Clinical Behavioral Measures

	HC			IBS			T-value	p-value
	N	Mean	sd	N	Mean	sd
Sex (Male/Female)	7/9			8/8
Bowel Habit
Constipation				7
Diarrhea				4
Alternating				0
Unspecified				1
Mixed				4
Age	16	38.81	10.13	16	36.31	10.18	0.70	.492
Hospital Anxiety and Depression (HAD)
Anxiety (0–21)	16	3.06	3.40	16	4.00	3.98	0.72	.479
Depression (0–21)	16	1.00	1.71	16	2.31	2.85	1.58	.124
Patient Health Questionnaire (PHQ- 15)	16	1.88	2.25	16	8.06	3.38	6.10	.001**
Visceral Sensitivity Index (VSI)	16	2.50	5.53	16	31.19	15.10	7.14	.002**
Pain Vigilance and Awareness Questionnaire (PVAQ)	16	37.75	19.59	16	40.42	11.37	0.47	.641
Early Traumatic Inventory (ETI-SR) (0–27)
ETI General Score	16	2.00	1.51	16	2.38	2.60	0.50	.622
ETI Physical Score	16	1.81	2.01	15	1.53	1.89	0.40	.693
ETI Emotional Score	16	1.50	2.10	16	1.38	1.89	0.18	.861
ETI Sexual Score	16	0.25	0.78	15	0.33	0.72	0.31	.760
Perceived Stress Scale (PSS)	16	7.06	6.49	16	12.25	8.58	1.93	.063
Bowel Symptom Questionnaire (BSQ)
BSQ bloating (0–20)				16	12.81	4.59
BSQ Abdominal pain (0–20)				16	10.81	4.34
BSQ Usual symptom severity (0–5)				16	3.06	0.57
BSQ Duration of symptoms (yrs)				15	12.20	8.55
BSQ Age of Onset				15	23.73	9.05

Questionnaires: HAD: Hospital Anxiety and Depression; PHQ: Patient Health Questionnaire; VSI: Visceral Sensitivity Index; PVAQ: Pain Vigilance and Awareness Questionnaire; ETI-SR: Early Traumatic Inventory; PSS: Perceived Stress Scale; Bowel Habit (Constipation, Diarrhea, Alternating, Unspecified, Mixed); BSQ: Bowel Symptom Questionnaire and consists of the following subscales: 1. BSQ Bloating in the Past week (0–20); 2. BSQ Abdominal Pain in the Past week (0–20); 3. BSQ Usual Symptom Severity: 1=None; 2=Mild; 3=Moderate; 4=Severe; 5=Very Severe; 5. BSQ Symptom Duration in years (derived from onset of symptoms); and 6. BSQ: Age of symptom onset

Abbreviations: N= sample size; sd: standard deviation; HC, healthy controls; IBS, irritable bowel syndrome

Significance p<.05*,

p<.005**