Table 1.
Baseline data of subjects in different groups
| Variable | Control N=20 | Smokers with COPD (N=45)
|
||
|---|---|---|---|---|
| Total (N=45) | Group 1 (N=24) | Group 2 (N=21) | ||
| Age (years) | 58.7±6.4 | 62.3±7.0 | 61.2±6.0 | 63.6±7.9 |
| BMI (kg/m2) | 25.1±2.9 | 24.3±2.8 | 25.0±1.9 | 23.5±3.4 |
| Smoking index (pack-years) | 32.2±15.4 | 36.4±17.4 | 40.8±19.0 | 30.9±13.6 |
| FEV1%pred | 100.4±12.3 | 55.0±18.5** | 69.7±9.9 | 38.2±9.4## |
| RV/TLC % | 35.5±8.9 | 52.7±12.4** | 43.9±7.2 | 63.8±7.8## |
| Inhaled corticosteroid | – | 15 (33.3%) | 3 (12.5%) | 12 (57.1%)## |
| Inhaled bronchodilator | – | 42 (93.3%) | 21 (87.5%) | 21 (100%) |
| GOLD classification | – | A 12 (26.7%) | A 12 (50%) | – |
| – | B 12 (26.7%) | B 12 (50%) | – | |
| – | C 8 (17.8%) | – | C 8 (38.1%) | |
| – | D 13 (28.9%) | – | D 13 (61.9%) | |
Notes: Continuous variables are presented as mean ± standard deviation, and categorical variables are shown as n (%).
**
P<0.01 represented the comparison between COPD and control.
##
P<0.01 represented the comparison between group 1 and group 2; – denoted that it was not applicable. COPD patients included two subgroups: group 1 (FEV1%pred ≥50%) and group 2 (FEV1%pred <50%).
Abbreviations: BMI, body mass index; GOLD, Global Initiative on Obstructive Lung Disease; FEV1, forced expiratory volume in 1 s; RV, residual capacity; TLC, total lung capacity.