Figure 9. HGF/MET inhibition suppresses both spontaneous and angiogenesis inhibitor-induced metastatic spreading in human HGF knock-in SCID mice.
A. HCT-116-luc and HT-29-luc hepatic metastases were determined by ex vivo bioluminescence (EVBL) analysis of explanted livers. B. HCT-116-luc and HT-29-luc pulmonary metastases were determined by EVBL analysis of explanted lungs. Values represent mean ± SEM. Statistical significance was calculated using a Student's T-test (n = 7).