Table 2. MRI findings for 60 patients before and after treatment by IAC.
MRI features | Before IAC | After IAC | P value |
---|---|---|---|
Location | |||
Tumor with totally or partially covering the optic disk | 45 | 3 | |
Tumor with distance of the tumor to the optic disk less than 2 mm | 11 | 14 | < 0.01 |
Tumor with distance of the tumor to the optic disk more than 2 mm | 4 | 43 | |
Maximum diameter of tumor (mean values, cm) | 1.55 ± 0.26 | 0.66 ± 0.36 | < 0.001 |
D (n = 50) | 1.54 ± 0.24 | 0.61 ± 0.35 | < 0.001 |
E (n = 10) | 1.60 ± 0.36 | 0.87 ± 0.38 | < 0.001 |
Thickness (mean values, cm) | 1.41 ± 0.34 | 0.39 ± 0.34 | < 0.001 |
D (n = 50) | 1.42 ± 0.34 | 0.34 ± 0.30 | < 0.001 |
E (n = 10) | 1.36 ± 0.35 | 0.61 ± 0.45 | < 0.001 |
Maximum cross-sectional area (mean values, cm2) | 1.51 ± 0.45 | 0.29 ± 0.23 | < 0.001 |
D (n = 50) | 1.49 ± 0.44 | 0.24 ± 0.20 | < 0.001 |
E (n = 10) | 1.65 ± 0.50 | 0.53 ± 0.26 | < 0.001 |
ADC (mean values, 10−3 mm2/s) | 0.94 ± 0.24 | 2.24 ± 0.40 | < 0.001 |
D (n = 50) | 0.92 ± 0.22 | 2.24 ± 0.43 | < 0.001 |
E (n = 10) | 1.00 ± 0.33 | 2.22 ± 0.27 | < 0.001 |
Enhancement | |||
Non-enhancement | 0 | 55 | |
Mild | 9 | 5 | < 0.001 |
Moderate | 51 | 0 | |
Enhancement of laminar optic nerve, No. (%) | 6 (10) | 0 (0) | < 0.001 |
IAC = intra-arterial chemotherapy.
ADC = apparent diffusion coefficient.
All the count data in the table are patient numbers.