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. 2017 Mar 21;8(24):38413–38425. doi: 10.18632/oncotarget.16423

Table 2. MRI findings for 60 patients before and after treatment by IAC.

MRI features Before IAC After IAC P value
Location
 Tumor with totally or partially covering the optic disk 45 3
 Tumor with distance of the tumor to the optic disk less than 2 mm 11 14 < 0.01
 Tumor with distance of the tumor to the optic disk more than 2 mm 4 43
Maximum diameter of tumor (mean values, cm) 1.55 ± 0.26 0.66 ± 0.36 < 0.001
 D (n = 50) 1.54 ± 0.24 0.61 ± 0.35 < 0.001
 E (n = 10) 1.60 ± 0.36 0.87 ± 0.38 < 0.001
Thickness (mean values, cm) 1.41 ± 0.34 0.39 ± 0.34 < 0.001
 D (n = 50) 1.42 ± 0.34 0.34 ± 0.30 < 0.001
 E (n = 10) 1.36 ± 0.35 0.61 ± 0.45 < 0.001
Maximum cross-sectional area (mean values, cm2) 1.51 ± 0.45 0.29 ± 0.23 < 0.001
 D (n = 50) 1.49 ± 0.44 0.24 ± 0.20 < 0.001
 E (n = 10) 1.65 ± 0.50 0.53 ± 0.26 < 0.001
ADC (mean values, 10−3 mm2/s) 0.94 ± 0.24 2.24 ± 0.40 < 0.001
 D (n = 50) 0.92 ± 0.22 2.24 ± 0.43 < 0.001
 E (n = 10) 1.00 ± 0.33 2.22 ± 0.27 < 0.001
Enhancement
 Non-enhancement 0 55
 Mild 9 5 < 0.001
 Moderate 51 0
Enhancement of laminar optic nerve, No. (%) 6 (10) 0 (0) < 0.001

IAC = intra-arterial chemotherapy.

ADC = apparent diffusion coefficient.

All the count data in the table are patient numbers.