Table 1. Relationship between the variant RON deletion exon 2 and clinicopathologic features of CRC patients.
| Characteristic | SummaryCase no.(%) | Ron200bExpression | Ron200-350cExpression | Ron200+350dExpression | |||
|---|---|---|---|---|---|---|---|
| Caseno.(%) | P valuea | Caseno.(%) | P valuea | Caseno. (%) | P valuea | ||
| Age | 0.918 | 0.978 | 0.932 | ||||
| ≤58 yrs | 22(32.8) | 13(19) | 2(3) | 11(16) | |||
| >58 yrs | 45(67.2) | 26(39) | 4(6) | 22(33) | |||
| Gender | 0.514 | 0.660 | 0.695 | ||||
| male | 39(58.2) | 24(36) | 4(6) | 20(30) | |||
| female | 28(41.8) | 15(22) | 2(3) | 13(19) | |||
| Histologicdifferentiation | 0.756 | 0.501 | 0.935 | ||||
| well | 48(71.6) | 27(40) | 4(6) | 23(34) | |||
| moderate | 15(22.4) | 9(13) | 1(1) | 8(12) | |||
| poor | 4(6.0) | 3(4) | 1(1) | 2(3) | |||
| Tumor location | 0.819 | 0.833 | 0.729 | ||||
| colon | 25(37.3) | 15(22) | 2(3) | 13(19) | |||
| rectum | 42(62.7) | 24(36) | 4(6) | 20(30) | |||
| T classification | 0.045 | 0.978 | 0.046 | ||||
| T1-3 | 22(32.8) | 9(13) | 2(3) | 7(10) | |||
| T4 | 45(67.2) | 30(45) | 4(6) | 26(39) | |||
| N classification | 0.220 | 0.787 | 0.172 | ||||
| N0 | 30(44.8) | 15(22) | 3(4) | 12(18) | |||
| N1-3 | 37(55.2) | 24(36) | 3(4) | 21(31) | |||
| M classification | 0.391 | 0.369 | 0.174 | ||||
| M0 | 62(92.5) | 37(55) | 5(7) | 32(48) | |||
| M1 | 5(7.5) | 2(3) | 1(1) | 1(1) | |||
| Clinical stage | 0.220 | 0.787 | 0.172 | ||||
| I-II | 30(44.8) | 15(22) | 3(4) | 12(18) | |||
| III-IV | 37(55.2) | 24(36) | 21(31) | 21(31) | |||
a Chi-Square test. Bold value were high light the significant value (p<0.05).
b Ron200, Electrophoresis in 200 bp ban.
c Ron200-350, Electrophoresis in 200 bp ban expect the 350 bp ban.
d Ron200+350, Electrophoresis in 200 bp and 350 bp ban.