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. 2017 Mar 27;8(24):39143–39153. doi: 10.18632/oncotarget.16609

Figure 1. Virtual ligand screening and MST assay identifies the binding of ilaprazole to TOPK.

Figure 1

(a) Chemical structures of PPIs. (b) Detailed view of ilaprazole binding in the ligand binding pocket. (c) Overlay of one monomer of the TOPK–ilaprazole binary complex. (d) Measurement of affinity between screened drugs with TOPK by MST, and the resulting binding curves were shown.