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. 2017 Apr 7;8(24):39296–39308. doi: 10.18632/oncotarget.16945

Table 1. The six SNPs significantly (P < 1.21 × 106) associated with BMI in the EWAS.

Gene dbSNP Nucleotide (amino acid) substitutiona Chromosome: position MAF (%) P (genotype)
rs633715 T/C 1: 177883445 22.0 8.33 × 10−8
rs543874 A/G 1: 177920345 21.9 1.36 × 10−7
FTO rs1421085 T/C 16: 53767042 19.1 5.37 × 10−7
FTO rs1558902 T/A 16: 53769662 19.1 6.67 × 10−7
FTO rs8050136 C/A 16: 53782363 19.2 1.08 × 10−6
FTO rs9939609 T/A 16: 53786615 19.3 1.13 × 10−6

The relation of genotypes of SNPs to BMI was evaluated by linear regression analysis. aMajor allele/minor allele.