Table 2. Summary of OR and 95%CI for association between rs144848 polymorphism and susceptibility to cancer.
Variable per SNP | I2 (%) | p for heterogeneity | OR (95% CI) | p value | p for publication bias | Effects model | Sensitive analysis | |||
---|---|---|---|---|---|---|---|---|---|---|
exclude | OR (95% CI) | p value | p for publication bias | |||||||
H allele vs N allele | 7.0 | 0.345 | 1.044 (1.021-1.068) | <0.001a | 0.045 | fixed | [36] | 1.053 (1.028-1.080) | <0.001a | 0.143 |
NH vs NN | 0.0 | 0.491 | 1.037 (1.006-1.069) | 0.018a | 0.147 | fixed | [36] | 1.048 (1.014-1.082) | 0.005a | 0.352 |
HH vs NN | 16.8 | 0.183 | 1.104 (1.044-1.168) | 0.001a | 0.066 | fixed | [46] | 1.125 (1.060-1.194) | <0.001a | 0.148 |
Dominant model | 0.0 | 0.470 | 1.047 (1.018-1.078) | 0.002a | 0.069 | fixed | [36] | 1.059 (1.026-1.092) | <0.001a | 0.069 |
Recessive model | 16.8 | 0.184 | 1.086 (1.028-1.146) | 0.003a | 0.114 | fixed | [46] | 1.102 (1.040-1.168) | 0.001a | 0.214 |
a Statistically significant