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Phenotype of Cre promotor Ttr-driven knockout embryos
| NTD [n (%)] |
|||||
|---|---|---|---|---|---|
| Dam | E | Total embryos | Resorption | flox/+;cre−/− | flox/−;cre+/−a |
| flox/−;cre−/− | |||||
| flox/+;cre+/− | |||||
| 8 |
9.5 |
66 |
6 |
4/21 (33.3) |
|
| 12 |
13.5 |
100 |
7 |
0/75 (0) |
2/25 (8.0) |
| 3 | 18.5 | 25 | 3 | 0/21 (0) | 0/4 (0.0) |
Conditional knockout.
