Table 4.
Major colon lipid groups identified in heirarchical cluster analysis to differ by diet or carcinogen treatment of rats. The lipid groups for Experiment A refer to lipodomic analysis of tumor tissues from carcinogen-treated rats and normal tissues from control rats fed either Western fat or fish oils diet. Lipid groups for Experiment B refer to lipodomic analysis of normal tissues from control rats and normal tissues from carcinogen-treated rats. These lipids groups are annotated in the heat maps generated from hierarchical cluster analysis as shown in the accompanying Data in Brief article [28]). The lipids in each group are sorted alphabetically. Abbreviations: cardiolipin, CL; diglycerides, DG; free fatty acids, FFA; monoglycerides, MG; phosphatidylcholine, PC; phosphatidylethanolamine, PE; PG; phosphatidylinositol, PI; phosphatidylserine, PS; Sphingomyelin, SM; triglycerides, TG.
| Experiment A: Group 1 Increased in tumors vs. normal tissue of control rats | Experiment A: Group 2 Decreased by fish oil vs. Western fat diet | Experiment A: Group 3 & 4 Increased by fish oil vs. Western fat diet | Experiment B: Group 1 Increased by fish oil diet vs. Western fat diet | Experiment B: Group 2 Decreased by fish oil vs. Western fat diet | Experiment B: Group 3 Increased by carcinogen treatment vs. no carcinogen |
|---|---|---|---|---|---|
| CL 74:3 | CE 22:4 | CE 22:1 | CL 72:8 | CL 68:2 | FFA 16:0 |
| CL 74:6 | lysoPE 22:4 | CL 68:1 | CL 74:9 | CL 74:6 | FFA 18:0 |
| CL 78:3 | plasmenyl-PE 40:4 | CL 72:7 | CL 82:9 | CL 76:9 | FFA 18:1 |
| FFA 16:0 | plasmenyl-PE 40:4 | CL 72:8; | DG 32:6 | DG 40:4 | FFA 18:2 |
| FFA 18:0 | plasmenyl-PE 38:4 | CL 76:10 | DG 34:5 | FFA 22:3 | FFA 20:0 |
| FFA 18:1 | PC 40:4 | CL 78:9 | DG 34:6 | FFA 24:3 | FFA 20:1 |
| FFA 18:2 | DG 40:4 | DG 34:6 | DG 36:5 | lysoPC 22:4 | FFA 20:2 |
| FFA 20:0 | PE 40:4 | DG 36:6 | DG 38:6 | lysoPE 20:4 | FFA 20:4 |
| FFA 20:1 | PC 36:4 | DG 38:6 | DG 40:6 | lysoPE 22:4 | FFA 22:1 |
| FFA 20:2 | PC 38:4 | DG 38:7 | DG 40:7 | PC 36:4 | FFA 22:2 |
| FFA 20:4 | DG 40:7 | lysoPC 14:0 | PC 38:4 | FFA 24:1 | |
| FFA 22:0 | lysoPC 20:5 | lysoPC 15:0 | PC 40:4 | FFA 24:2 | |
| FFA 22:1 | lysoPE 20:5 | lysoPC 16:1 | PC 42:5 | lysoPC 18:0 | |
| FFA 22:2 | PA 38:5 | lysoPC 17:1 | PE 38:2 | lysoPC 18:1 | |
| FFA 24:0 | PC 31:1 | lysoPC 18:2 | PE 40:4 | lysoPC 20:2 | |
| FFA 24:1 | PC 34:5 | lysoPC 19:0 | PG 38:5 | MG 18:1 | |
| FFA 24:2 | PC 35:5 | lysoPC 23:0 | PG 40:5 | MG 18:2 | |
| FFA 24:3 | PC 36:5 | lysoPE 19:0 | PG 40:6 | plasmenyl-PC 18:0 | |
| lysoPE 17:1 | PC 36:6 | lysoPE 22:6 | PG 42:8 | plasmenyl-PC 20:0 | |
| lysoPE 18:0 | PC 36:7 | lysoPE 23:0 | PG 44:10 | ||
| lysoPE 20:0 | PC 37:6 | PC 31:0 | PG 44:9 | ||
| lysoPE 21:0 | PC 38:6 | PC 32:1 | PI 36:4 | ||
| lysoPE 22:1 | PC 38:7 | PC 33:0 | plasmenyl-PE 36:4 | ||
| lysoPE 24:1 | PC 38:8 | PC 33:1 | plasmenyl-PE 38:3 | ||
| lysoPE 26:0 | PC 38:9 | PC 34:2 | plasmenyl-PE 38:4 | ||
| PC 29:0 | PC 40:10 | PC 34:5 | plasmenyl-PE 40:3 | ||
| PC 30:0 | PC 44:12 | PC 36:2 | plasmenyl-PE 40:4 | ||
| PC 30:1 | PE 35:1 | PC 36:5 | PS 36:4 | ||
| PC 32:0 | PE 36:5 | PC 36:6 | PS 38:4 | ||
| PC 32:1 | PE 36:6 | PC 37:5 | PS 40:4 | ||
| PC 33:0 | PE 37:5 | PC 37:6 | PS 42:5 | ||
| PC 33:1 | PE 37:6 | PC 38:5 | TG 42:0 | ||
| PC 34:1 | PE 38:6 | PC 38:6 | TG 54:0 | ||
| PC 34:2 | PE 40:5 | PC 38:7 | |||
| PC 35:1 | PE 40:6 | PC 40:7 | |||
| PC 36:0 | PG 34:2 | PC 40:8 | |||
| PC 36:1 | PG 42:11 | PC 42:1 | |||
| PC 36:3 | PG 44:12 | PC 42:10 | |||
| PC 38:1 | PI 38:5 | PC 42:11 | |||
| PC 38:2 | PI 38:6 | PC 42:2 | |||
| PC 40:0 | plasmenyl-PE 30:0 | PE 36:5 | |||
| PC 40:1 | plasmenyl-PE 36:2 | PE 36:6 | |||
| PC 40:3 | plasmenyl-PE 36:5 | PE 38:5 | |||
| PC 40:7 | plasmenyl-PE 38:6 | PE 38:6 | |||
| PC 40:8 | plasmenyl-PE 40:5 | PE 38:7 | |||
| PC 42:1 | plasmenyl-PE 40:6 | PE 40:5 | |||
| PC 42:2 | plasmenyl-PE 42:6 | PE 40:6 | |||
| PC 42:3 | PS 38:4 | PG 33:0 | |||
| PC 44:3 | SM 36:2 | PG 40:7 | |||
| PC 44:5 | SM 40:2 | PG 44:11 | |||
| PE 30:0 | TG 49:1 | PG 44:12 | |||
| PE 32:0 | TG 49:2 | PI 32:1 | |||
| PE 32:1 | TG 51:4 | PI 34:1 | |||
| PE 33:0 | TG 52:6 | PI 34:2 | |||
| PE 36:0 | TG 52:7 | PI 36:1 | |||
| PE 38:1 | TG 53:5 | PI 36:2 | |||
| PE 40:1 | TG 53:6 | PI 38:3 | |||
| PE 40:2 | TG 54:7 | PI 38:5 | |||
| PE 41:1 | TG 54:8 | PI 40:6 | |||
| PE 42:1 | TG 55:6 | plasmenyl-PE 34:1 | |||
| PE 42:2 | TG 55:7 | plasmenyl-PE 34:2 | |||
| PE 42:3 | TG 56:7 | plasmenyl-PE 36:1 | |||
| PE 43:1 | TG 56:8 | plasmenyl-PE 36:2 | |||
| PE 44:2 | TG 56:9 | plasmenyl-PE 36:5 | |||
| PE 44:3 | TG 57:6 | plasmenyl-PE 38:5 | |||
| PE 44:4 | TG 57:7 | plasmenyl-PE 38:6 | |||
| PG 32:0 | TG 58:1 | plasmenyl-PE 40:5 | |||
| PG 34:1 | TG 58:10 | plasmenyl-PE 40:6 | |||
| PG 40:7 | TG 58:11 | plasmenyl-PE 42:6 | |||
| PG 40:8 | TG 58:7 | PS 34:1 | |||
| PG 42:10 | TG 58:8 | PS 35:1 | |||
| PG 44:11 | TG 58:9 | PS 36:2 | |||
| PI 34:2 | TG 60:1 | PS 38:3 | |||
| PI 36:1 | TG 60:10 | PS 38:5 | |||
| PI 36:2 | TG 60:13 | PS 38:6 | |||
| PI 36:4 | TG 60:7 | PS 40:5 | |||
| PI 38:3 | TG 60:8 | PS 40:6 | |||
| plasmenyl-PE 32:0 | TG 60:9 | SM 37:1 | |||
| plasmenyl-PE 32:1 | SM 39:1 | ||||
| plasmenyl-PE 34:1 | SM 44:2 | ||||
| plasmenyl-PE 36:1 | TG 49:1 | ||||
| plasmenyl-PE 38:1 | TG 49:2 | ||||
| plasmenyl-PE 42:5 | TG 51:4 | ||||
| TG 52:6 | |||||
| TG 52:6 | |||||
| TG 52:7 | |||||
| TG 53:4 | |||||
| TG 53:5 | |||||
| TG 53:6 | |||||
| TG 53:7 | |||||
| TG 54:7 | |||||
| TG 54:8 | |||||
| TG 55:7 | |||||
| TG 56:10 | |||||
| TG 56:6 | |||||
| TG 56:7 | |||||
| TG 56:8 | |||||
| TG 56:9 | |||||
| TG 58:10 | |||||
| TG 58:11 | |||||
| TG 58:12 | |||||
| TG 58:7 | |||||
| TG 58:8 | |||||
| TG 58:9 | |||||
| TG 60:11 | |||||
| TG 60:12 | |||||
| TG 60:9 | |||||
| TG 62:13 |