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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Curr Pediatr Rev. 2017;13(1):24–33. doi: 10.2174/1573396313666161116094916

Table 1.

Impact of Cancer Treatment Across Development

Psychosocial Challenges Cognitive Challenges Behavioral Result
Infant/Toddlers (0–2 years) Difficulties with regular feeding, comfort, and cares in can lead to caregiver mistrust and attachment disruptions. Developing sensory and motor curiosities can be particularly disrupted by pain, nausea, and discomfort of treatment. Worsening abilities to self-soothe and be soothed. Increased irritability with touch or aversion to it.
Preschool(3–5 years) Failure to develop sense of personal control over environment and physical tasks such as toileting, feeding self, walking can lead to fearfulness, anxiety, doubt, frustration, and guilt. Imagination and magical thinking develops. Fantasy and fears can be complex around physical and environmental difficulties of treatment. Complex abstract thought about death is still limited. Temper tantrums and procedural resistance can develop when unable to have control, experiencing inconsistent limits/messages, and changing routines. Token economy can be helpful motivator.
School Age(6–11 years) Disruptions in school, sports, and activities valued by family units can lead to sense of inferiority and guilt/shame. More concrete understanding of treatment including length, number of treatments, and developing understanding of death. Frequent aversion to medicine, nutrition, and other differences compared to family members due to sense of unfairness and disruption of normalcy.
Adolescents (12–18 years) Inability to find acceptance in peer groups and explore different roles can lead to frustration and confusion. Profound loneliness and isolation can develop without intimate peer relationships. Abstract reasoning and theoretical concepts of death develops. Concepts learned in one context can be applied to others. Critical thinking, planning, and agency in care are possible. Risk-taking and non-adherence due to sense of invincibility or active denial. Behavior often for the benefit of social/peer values and activities with less influence or care about family values