Table 3.
Gene | CRBL | FCTX | HIPP | MEDU | OCTX | PUTM | SNIG | TCTX | THAL | WHMT |
---|---|---|---|---|---|---|---|---|---|---|
BCHE | 0.29 | 0.98 | 0.17 | 0.53 | 0.015 | 0.27 | 0.87 | 0.72 | 0.001 | 0.34 |
PDCD10 | 0.09 | 0.003 | 0.61 | 0.82 | 0.52 | 0.64 | 0.62 | 0.41 | 0.90 | 0.67 |
SERPINI1 | 0.007 | 0.11 | 0.014 | 0.22 | 0.035 | 0.68 | 0.66 | 0.47 | 0.39 | 0.26 |
WDR49 | 0.73 | 0.80 | 0.05 | 0.79 | 0.003 | 0.54 | 0.95 | 0.23 | 0.22 | 0.70 |
ZBBX | 0.27 | 0.004 | 0.93 | 0.61 | 0.71 | 0.37 | 0.52 | 0.73 | 0.48 | 0.56 |
Note: A Bonferroni’s correction was used to adjust for multiple testing; bold font denotes P-values that withstood this correction. In the Braineac database (http://www.braineac.org/), rs11720469 was used for expression quantitative trait locus analysis (N = 134 individuals of European Ancestry) of 10 different regions of the brain, including: cerebellar cortex (CRBL), frontal cortex (FCTX), hippocampus (HIPP), medulla (specifically inferior olivary nucleus; MEDU), occipital cortex (specifically primary visual cortex; OCTX), putamen (PUTM), substantia nigra (SNIG), thalamus (THAL), and intralobular white matter (WHMT). A detailed description of the samples used in the study, tissue processing and dissection is provided in Trabzuni et al.43