Figure 1. The components of the amylin receptor complex are expressed in the LDTg.
Micropunches of LDTg-enriched tissue (n=6) show expression that gene expression of CTRa is ~5 fold higher than CTRb (A), and gene expression of RAMP1 is ~2-fold higher than RAMP2 and ~13-fold higher than RAMP3 (B). Immunohistochemical data using CTR to label amylin receptor-expressing cells (n=6) show dense labeling of cell bodies and projections in the caudal LDTg (C, D). The dotted box in C (20×) represents the field of view in D (20× with a 2× optical zoom). * indicates significance by repeated measures ANOVA (p<0.05).