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. 2017 Jun 23;13:661–666. doi: 10.1016/j.dib.2017.06.032

Fig. 1.

Fig. 1

Lipidomic analysis of distal colon tissue. Shown are the results of hierarchical cluster analysis of lipids that differed significantly by carcinogen treatment or diet type, after correction for false discovery rates. The lipid groups for Experiment A refer to a lipidomic analysis of tumor tissues from carcinogen-treated rats and normal tissues from control rats. The rats in either case were fed either a Western fat or fish oil diet. Lipid groups for Experiment B refer to lipidomic analysis of normal tissues from control rats and normal tissues from carcinogen-treated rats. The annotated lipid groups highlight those lipids that were altered by either 1) the fish oil diet versus the Western fat diet consistently in all samples across tissue type or to 2) those lipids that were consistently altered by tissue type without regard to diet. Abbreviations: cardiolipin, CL; diglycerides, DG; free fatty acids, FFA; monoglycerides, MG; phosphatidylcholine, PC; phosphatidylethanolamine, PE; PG; phosphatidylinositol, PI; phosphatidylserine, PS; Sphingomyelin, SM; triglycerides, TG. Interpretation of these results is shown in the accompany research paper [1]. A. Normal colon tissue from control rats and tumor tissue from rats treated with carcinogen. In each group, rats were fed either the Western fat (control) or fish oil diet. Lipids that differed significantly by group, after correction for false discovery rates, are shown. Legend: Blue, normal colon from control rats fed the Western fat diet; Green, normal colon from control rats fed the fish oil diet; Red, tumor tissue from carcinogen-treated rats fed the Western fat diet; and Black, tumor tissue from carcinogen-treated rats fed the fish oil diet. B. Grossly normal colon tissue from rats treated with carcinogen (AOM and DSS) or from control rats, fed either the Western fat (control) or fish oil diet. Legend: Blue, normal colon from control rats fed the Western fat diet; Green, normal colon from carcinogen-treated rats fed the Western fat diet; Red, normal colon from control rats fed the fish oil diet; Black, normal colon from carcinogen-treated rats fed the fish oil diet.