Table 2. Associations between FGF21 and Cardiovascular Diseases.

CV end-point	Result	Reference
CV mortality	Elevated serum FGF21 predicted combined morbidity and mortality in T2DM	[27]
Total CV outcomes	Elevated plasma FGF21	[21]
CHD	Elevated serum FGF21	[22]
Carotid artery IMT	Elevated serum FGF21	[23,24]
Arterial stiffness	Brachial-ankle pulse wave velocity independently associated with serum FGF21	[26]
LEAD	Elevated serum FGF21	[25]

FGF21, fibroblast growth factor 21; CV, cardiovascular; T2DM, type 2 diabetes mellitus; CHD, coronary heart disease; IMT, intima-media thickness; LEAD, lower extremity atherosclerotic disease.