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. 2017 Jul 10;7:5008. doi: 10.1038/s41598-017-05264-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Enzymes identified in both types of vesicles and functional metabolic pathways. (A) The columnar histogram represents distribution of enzymes identified in both types of vesicles according to enzyme class. The Venn diagram represents comparative analysis of the total number of enzymes identified in both types of vesicles. (B) The main pathways and functional groups of proteins identified in both types of vesicles. External histogram—the proteins identified in ETBF OMVs; internal histogram—the proteins identified in NTBF OMV. The number of identified proteins involved in a particular metabolic pathway is represented as the percentage of the total number of proteins identified in ETBF or NTBF OMVs.