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. 2017 Jul 10;7:4982. doi: 10.1038/s41598-017-05226-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Store-operated calcium entry (SOCE) inhibitor 2-APB attenuates the TGF-β2 effect on Fgf23 transcript levels in UMR106 cells. Arithmetic means ± SEM (n = 4) of Fgf23 mRNA abundance (relative to Tbp mRNA) in UMR106 cells incubated without (white bars) or with TGF-β2 (black bars, 10 ng/ml) in the absence or presence of SOCE inhibitor 2-APB (25 μM) for 24 h. **p < 0.01 indicates significant difference from the absence of TGF-β2. ^### p < 0.001 indicates significant difference between cells treated with TGF-β2 alone (2^nd bar) and cells treated with TGF-β2 and 2-APB (4^th bar) (ANOVA).