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. 2017 Jul 10;7:4955. doi: 10.1038/s41598-017-05285-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relationships between amyloid load quantified from in vivo Gd-stained MR images, and from amyloid-stained histological sections (BAM10) (A) or from iron-stained histological sections (Perls-DAB) (B). Amyloid load measured from Gd-stained MRI showed a correlation with BAM10 staining (R² = 0.82; p < 0.01) but was not correlated with Perls-DAB staining (R² = 0.35; p > 0.05).