Table 1.
Comparative proteomic and transcriptomic analyses of antimicrobial proteins in SPC-HAxTCR-HA vs. SPC-HA lungs.
| Gene symbol | Protein | Transcript Cluster ID | SwissProt Accession ID | Analyses | |
|---|---|---|---|---|---|
| BALFome | Microarray (FC) | ||||
| Pigr | Polymeric immunoglobulin receptor | 10531126 | O70570 | x | x (3.4) |
| Igj | Immunoglobulin joining chain | 10531126 | P01592 | x | x (13.6) |
| Igh-VJ558 | Immunoglobulin alpha chain C region | 10402864 | P01878 | x | x (3.9) |
| Ltf | Lactotransferrin | P08071 | x | ||
| Camp | Cathelin-related antimicrobial peptide | P51437 | x | ||
| Sftpa1 | Pulmonary surfactant-associated protein A | P35242 | x | ||
| Ighm | Immunoglobulin mu chain C region | P01872 | x | ||
| Pglyrp1 | Peptidoglycan recognition protein 1 | 10550509 | x (4.4) | ||
| C1qc | Complement component 1, q subcomponent, C chain | 10517513 | x (3.1) | ||
| C1qb | Complement component 1, q subcomponent, beta polypeptide | 10517508 | x (2.8) | ||
| Cfb | Complement factor B | 10450325 | x (2.7) | ||
| C1qa | Complement component 1, q subcomponent, alpha polypeptide | 10517517 | x (2.7) | ||
| Cfp | Complement factor properdin | 10603860 | x (2.5) | ||
| Lcn2 | Lipocalin 2 | 10481627 | x (2.0) | ||
| Reg3g | Regenerating islet-derived 3 gamma | 10545569 | x (5.3) | ||
Definition of abbreviations: FC = fold change, x = protein uniquely detected in SPC-HAxTCR-HA BALFome, also: transcript induced in SPC-HAxTCR-HA lungs.