Table 1.
Septic patients’ characteristics.
| Variables | Control (n = 60) | Sepsis (n = 60) |
|---|---|---|
| Age (years) | 52 ± 6 | 53 ± 11 |
| Sex (Male/Female) | 35/25 | 35/25 |
| Vital signs | ||
| Temperature (ÿC) | 36 ± 0.5 | 38.5 ± 1.1 |
| Respiratory Rate (bpm) | 16 ± 3 | 22 ± 5 |
| Heart Rate (bpm) | 74 ± 7 | 82 ± 14 |
| SBP (mm Hg) | 96 ± 7 | 115 ± 12 |
| DBP (mm Hg) | 75 ± 13 | 73 ± 18 |
| MAP (mm Hg) | 85 ± 13 | 90 ± 21 |
| Glasgow Coma Scale score | 15 | 14 ± 1.2 |
| Laboratory results | ||
| WBC (109/L) | 6.5 ± 3.7 | 13.2 ± 6.3* |
| Platelet (109/L) | 225 ± 34 | 196 ± 85 |
| PO2 | 85 ± 11 | 75 ± 12 |
| PO2/FiO2 (mm Hg) | 413 ± 22 | 325 ± 54 |
| Bilirubin (mg/dL) | 0.4 ± 0.1 | 0.9 ± 0.3* |
| Creatinine (mg/dL) | 0.5 ± 0.2 | 1.4 ± 0.6* |
| Bacteria Culture + | — | 39 |
| Gram+/− | — | 27/12 |
| Coagulation parameter | ||
| PT (s) | 13 ± 4.3 | 16.5 ± 11.4 |
| APTT (s) | 26.8 ± 5.2 | 33.5 ± 14 |
| Fibrinogen (g/L) | 3.2 ± 0.7 | 2.8 ± 1.7 |
| D-dimer (g/L) | 0.9 ± 0.5 | 8.1 ± 5.6* |
| DIC | — | 2 |
Values given in mean and SD. *P < 0.05 vs. control. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; WBC, white blood cell; PT, prothrombin time; APTT, activated partial thromboplastin time; DIC, disseminated intravascular coagulation.