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. 2017 Jul 10;7:4989. doi: 10.1038/s41598-017-05051-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of taurine on the body weight. The body weight was recorded on days 0, 7, 14, 21 and 28 of CUMS were applied. Ctr, control group; CUMS, CUMS group; Saline, i.p. saline; T1, i.p. 200 mg/kg taurine; T2, i.p. 500 mg/kg taurine; All data are expressed as means ± SE and were analyzed by repeated measures ANOVA with group and time as factors followed by Bonferroni’s multiple comparisons post hoc test (n = 10). *P < 0.003 vs. CUMS group; **P < 0.00067 vs. CUMS group. d means Cohen’s d, d = 0.20 was considered as small effect size, d = 0.50 was considered as medium effect size, d = 0.80 was considered as large effect size.