Table 2.

Tree topology test for the duplication timing between CTCF and CTCFL

Rank by log-likelihood (lnL)	Tree topology*	ΔlnL	pAU	pKH
1	(((((Amn,Sa),Amp),Te),Ch),CTCFL,Cy);	ML	0.924	0.499
2	((((Amn,(Sa,Amp)),Te),Ch),CTCFL,Cy);	0	0.925	0.501
3	(((((Amn,Amp),Sa),Te),Ch),CTCFL,Cy);	0	0.925	0.501
4	((((Amn,Amp),Sa),(Te,Ch)),CTCFL,Cy);	1.6	0.667	0.22
5	((((Amn,Sa),Amp),(Te,Ch)),CTCFL,Cy);	1.6	0.531	0.22
6	(((Amn,(Amp,Sa)),(Te,Ch)),CTCFL,Cy);	1.6	0.527	0.22
7	(((((Amn,Amp),Sa),Ch),Te),CTCFL,Cy);	1.6	0.376	0.212
8	((((Amn,(Amp,Sa)),Ch),Te),CTCFL,Cy);	1.6	0.378	0.212
9	(((((Amn,Sa),Amp),Ch),Te),CTCFL,Cy);	1.6	0.375	0.212
10	(((Amn,(Sa,(Ch,Te))),Amp),CTCFL,Cy);	1.9	0.55	0.267
106	(((((Amn,Amp),Sa),Te),CTCFL),Ch,Cy);	6.7	0.513	0.139
111	(((((Amn,Amp),Sa),CTCFL),Te),Ch,Cy);	7.3	0.496	0.134
122†	((((Amn,CTCFL),(Amp,Sa)),Te),Ch,Cy);	7.9	0.299	0.124
130	(((((Amn,CTCFL),Amp),Sa),Te),Ch,Cy);	8.8	0.02	0.095
139	(((((Amn,Amp),CTCFL),Sa),Te),Ch,Cy);	9.1	0.028	0.091
327‡	(((Amn,Amp),CTCFL),(Te,Ch),(Sa,Cy));	12.2	0.069	0.046

^*Amn, amniote CTCF; Amp, amphibian CTCF; Sa, sarcopterygian CTCF; Te, teleost CTCF; Ch, chondrichthyan CTCF; Cy, cyclostome CTCF.

^†The phylogenetic tree supporting an amniote CTCF-CTCFL monophyly with the highest pAU.

^‡The phylogenetic tree supporting a tetrapod CTCF-CTCFL monophyly with the highest pAU.Abbreviation: ML, maximum likelihood tree.