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RNA Foci Formation in SCA36 Patient iPSNs
(A) Sense RNA foci were detected in nucleus of SCA36 patient iPSNs by FISH analysis. Scale bar, 10 μm. (B) The RNA-foci-positive cell ratio. ***p < 0.001. Values are expressed as mean ± SEM from n = 3 clones. (C) Representative image showing RNA foci (arrows) and Islet1-positive motor neurons. Scale bar, 10 μm.
