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. 2017 Mar 31;143(8):1585–1596. doi: 10.1007/s00432-017-2402-x

Table 6.

Most frequent (≥5% in any group) laboratory abnormalities

Laboratory abnormalities Young, n (%) Middle age, n (%) Elderly, n (%) Old, n (%)
All grade Grade 3 or 4 All grade Grade 3 or 4 All grade Grade 3 or 4 All grade Grade 3 or 4
Total bilirubin ↑ 25 (10.3) 5 (2.1) 36 (7.3) 5 (1.0) 17 (5.7) 4 (1.3) 2 (3.8)
ALT ↑ 27 (11.1) 4 (1.6) 49 (9.9) 9 (1.8) 9 (3.0) 2 (0.7) 1 (1.9) 1 (1.9)
AST ↑ 14 (5.8) 1 (0.4) 26 (5.3) 4 (0.8) 11 (3.7) 1 (0.3)
Phosphate ↓ 13 (5.3) 6 (2.5) 48 (9.7) 15 (3.0) 15 (5.0) 3 (1.0) 1 (1.9)
Lipase ↑ 7 (2.9) 3 (1.2) 37 (7.5) 16 (3.2) 30 (10) 18 (6.0) 3 (5.8) 1 (1.9)
Hypertension 7 (2.9) 31 (6.3) 4 (0.8) 22 (7.3) 6 (2.0) 5 (9.6) 2 (3.8)

ALT alanine aminotransferase, AST aspartate aminotransferase