Table 7.

Cardiovascular adverse events (AEs) by age group

Cardiovascular AEs	Young (n = 243)	Adult (n = 494)	Elderly (n = 300)	Old (n = 52)	P value by Fisher’s exact test*
Cardiovascular events	2 (0.8%)	26 (5.3%)	30 (10%)	7 (13.5%)	<0.0001
Ischemic heart disease	1 (0.4%)	14 (2.8%)	17 (5.7%)	5 (9.6%)	0.0002
Peripheral arterial occlusive disease	1 (0.4%)	9 (1.8%)	9 (3.0%)	1 (1.9%)	0.12
Ischemic cerebrovascular event	0	4 (0.8%)	4 (1.3%)	1 (1.9%)	0.19

*P values provided are nominal, post hoc, and for descriptive purpose only; no multiplicity adjustments were made