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. 2017 Jul 11;8:1273. doi: 10.3389/fmicb.2017.01273

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Copyright © 2017 Carvalho, de Jong, Kloosterman, Kuipers and Saraiva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the central metabolic pathways of S. aureus grown on galactose and prolonged exposed to NO. Upregulated and downregulated pathways (cut-off > 2) are denoted with bold green and red arrows, respectively. Narrower green and red arrows indicate significantly altered expression, considering a cut-off between 1.5 and 2. The α-acetolactate synthase (alsS) and the NADP⁺, NADPH cofactors are highlighted in black and blue, respectively. Proposed pathways were reconstructed based on genome information (http://www.ncbi.nlm.nih.gov/genomes/lproks.cgi), literature and database surveys (KEGG, MetaCyc). BCAAs, branched-chain amino acids; BCFAs, branched-chain fatty acids; FA, fatty acids.