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. 2017 Jul 11;8:447. doi: 10.3389/fphar.2017.00447

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Copyright © 2017 Li, Du, Kong, Liu, Li, Lin, Jia, Yuan, Sun and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OPLS-DA analyses of metabolic profiles between control, model and the JHC groups for intestine, kidney, and spleen. Score plots (A) and color-coded coefficient loadings plots (D) for intestine (R² = 0.80, Q² = 0.63). Score plots (B) and color-coded coefficient loadings plots (E) for kidney (R² = 0.65, Q² = 0.49). Score plots (C) and color-coded coefficient loadings plots (F) for spleen (R² = 0.82, Q² = 0.56). Significantly changed metabolites were assigned in the loadings plots. Negative signals represent increased and positive signals represent decreased concentrations in model group. Symbols of • (black filled circles), (red filled squares), and (green filled rhombuses) represent the control, model, and JHC groups, respectively.

Inline graphic — OPLS-DA analyses of metabolic profiles between control, model and the JHC groups for intestine, kidney, and spleen. Score plots (A) and color-coded coefficient loadings plots (D) for intestine (R² = 0.80, Q² = 0.63). Score plots (B) and color-coded coefficient loadings plots (E) for kidney (R² = 0.65, Q² = 0.49). Score plots (C) and color-coded coefficient loadings plots (F) for spleen (R² = 0.82, Q² = 0.56). Significantly changed metabolites were assigned in the loadings plots. Negative signals represent increased and positive signals represent decreased concentrations in model group. Symbols of • (black filled circles), (red filled squares), and (green filled rhombuses) represent the control, model, and JHC groups, respectively.