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. 2017 Jul 11;5:65. doi: 10.3389/fcell.2017.00065

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Copyright © 2017 Benfeitas, Uhlen, Nielsen and Mardinoglu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chemical cycle of PRDXs, TXNs, and GSH. The redox state of PRDXs and TXN is indicated as follows: SH, reduced cysteine thiol; SOH, sulfenic acid; SO₂H, sulfinic acid; SS, disulfide. Orange dashed reactions highlight disulfide exchange between peroxiredoxins and thioredoxins and other proteins.