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. 2017 May 29;6(7):1720–1729. doi: 10.1002/cam4.1032

Figure 4.

Figure 4

200 mmol/L Tris–base treatment increases survival and decreases tumor formation in Mia PaCa‐2 orthotopic model. (A) Kaplan–Meyer survival curve illustrating that the animals treated with 200 mmol/L Tris–base survived significantly (P < 0.035) longer than the nontreated group.(B) Representative coronal T2‐weighted MRI images of the two cohorts, tap water and 200 mmol/L Tris–base (n = 5), showing the pancreatic tumor (red arrow). (C) Quantitative assessment of tumor volume at end point, showing a significant decrease in tumor volume in 200 mmol/L Tris–base‐treated group (**P = 0.004).Bar graph represents mean tumor volume ± SEM.